Fasting iron – serum

Blood Iron Level Test

A blood test performed to determine fasting iron levels in the serum. Iron plays a key role in the human body. It is essential for the proper functioning of the respiratory, circulatory, immune, and nervous systems.

What Does the Iron Test Involve?

The test involves drawing blood from a vein, which is then sent to the laboratory for analysis. The blood draw itself takes about 15 seconds.

If proper preparation for the test is not followed, the result may not be fully reliable. It is best to undergo the laboratory test in the morning.

Iron – Key Facts

Iron is one of the essential minerals. In the body, iron exists in three pools: storage (stored in the liver as ferritin and hemosiderin), transport (bound to transferrin), and functional (in hemoglobin and myoglobin).

Iron is responsible, among other things, for the proper functioning of the circulatory and respiratory systems. It is a component of hemoglobin, which transports oxygen to all body tissues. Iron also plays an important role in the nervous system, influencing cognitive functions and physical performance during exercise.

Iron levels depend on sex. In women, they are generally lower than in men (due to physiological differences). In women, iron levels decrease with age and during menstruation. Iron requirements also increase during pregnancy.

The best-absorbed sources of iron include meat and meat products, organ meats, poultry, fish, and eggs.
It is also beneficial to consume plant-based sources of iron, such as whole-grain cereals, nuts, seeds, dried fruits, legumes, and certain vegetables (including beets, Swiss chard, broccoli, green peas, spinach, parsley), as well as fruits (e.g., currants, avocado, raspberries).

When Should You Measure Blood Iron Levels?

An iron level test should be performed in the following situations:

• when symptoms of anemia appear, such as weakness, easy fatigue, pale skin, or dizziness;
• during pregnancy (increased iron requirements);
• in women with heavy menstrual bleeding;
• in patients with chronic diseases, including cancer, kidney disease, or impaired iron absorption in the gastrointestinal tract;
• in people following elimination diets (vegetarian or vegan diets);
• in individuals with a family history of iron overload;
• in patients after blood transfusions.

What Does the Test Diagnose?

High Iron Levels

High iron levels in the body, also known as hemochromatosis, can lead to several serious health problems. Hemochromatosis is a metabolic disorder that causes excessive absorption of iron from the diet, resulting in accumulation in internal organs such as the liver, heart, and pancreas.

Excess iron can occur in blood disorders, chronic liver diseases, and after blood transfusions.
Iron excess may also result from supplement overdose.

Symptoms of Excess Iron

Excess iron in the blood is toxic and can cause symptoms such as:

• weakness and fatigue,
• sleep problems and daytime sleepiness,
• low-grade fever,
• dry skin,
• hair loss,
• nausea,
• vomiting.

Low Iron Levels

Low iron levels in the body can lead to deficiency and cause a number of symptoms and serious health consequences. Iron is essential for the production of hemoglobin, which transports oxygen in the blood. Its deficiency can lead to iron-deficiency anemia, affecting the functioning of the entire body. In pregnant women, it may result in preterm birth and low birth weight.

Symptoms of Iron Deficiency

Iron deficiency may present as:

• fatigue and weakness,
• reduced concentration,
• pale skin,
• brittle or thinning hair,
• dry skin,
• characteristic vertical ridges on nails,
• dizziness and headaches,
• heart palpitations,
• a smooth or burning tongue.

Who Is at Particular Risk of Iron Deficiency?

• vegetarians and vegans,
• people following an unbalanced diet,
• athletes,
• pregnant women,
• women with heavy menstrual bleeding,
• women with short intervals between pregnancies,
• individuals with conditions causing impaired iron absorption,
• children with pica (abnormal eating behaviors),
• individuals with increased blood loss, e.g., after surgery,
• premature infants and children from multiple pregnancies.

Learn more:

• Iron – its role in the body, deficiency symptoms, and dosage
• Anemia – symptoms, causes, and treatment
• Anemia in pregnancy — diagnosis and treatment of anemia in pregnant women

How to Prepare for an Iron Test?

Proper preparation for an iron level test is essential to obtain accurate and reliable results:

• Avoid alcohol for 2–3 days before the test, as it may affect the results.
• The test should be performed on an empty stomach, which means the patient should refrain from eating for about 12 hours before the blood draw. The last meal should be consumed no later than 6:00 p.m. the previous day.
• On the morning of the test, you may drink up to one glass of water, but other beverages, including coffee and tea, should be avoided for at least 12 hours before the test.
• If the patient is taking medications, they should consult a doctor about whether they should be taken before the test.
• It is advisable to reduce stress and avoid intense physical activity on the day of the test. Resting in a seated position for 10–15 minutes before the blood draw is recommended.

Iron – Reference Ranges

The normal concentration of iron in the blood varies depending on sex and age. For adults, the reference range is typically 55–180 μg/dl (in women, values may be lower by approximately 20 μg/dl). During pregnancy, the demand for iron increases. These ranges may vary slightly depending on the laboratory performing the test.

Serum iron levels fluctuate and depend on many factors, including the time of day, menstrual cycle in women, diet, and the presence of chronic illnesses.

Iron Test Results

In the case of abnormal results, a medical consultation is recommended for proper interpretation. Iron test results should always be evaluated by a doctor in the context of other laboratory parameters and the patient’s clinical symptoms.

More information about receiving test results can be found HERE >>

Factors That May Affect Test Results

• iron supplementation,
• stress,
• physical activity,
• menstruation in women,
• alcohol.

Who Should You Consult About Abnormal Results?

• Hematologist
• Internist
• Gynecologist